Alprostadil;PGE1

CAS No:
745-65-3

Molecular Formula：

C20H34O5

Molecular Weight：

354.48

Storage:

Store in a tightly closed container in a cool, dry，Protect from moisture and direct sunlight.

Chemical name:

(1R,2R,3R)-3-Hydroxy-2-[(E)-(3S)-3-hydroxy-1-octenyl]-5- oxocyclopentaneheptanoic acid (USP)

Synonyms:

Prostaglandin E1

Download Product Documents

If documents are missing, please contact customer service.

Safety Data Sheet (SDS) (pdf)COA & Other Certificates (pdf)

Request a Quote

Technical Data

Appearance	White to off-white crystalline powder
Identification	HPLC retention time of sample complies with that of known sample
Specifific optical rotation	-60.0°~ -70.0°
Water	≤0.5%
Residue on Ignition	≤0.5%
Related Substances	Impurity A ≤1.5% Impurity B ≤ 0.5% Any other impurity ≤ 0.9% Total impurities ≤1.5%
Residual solvents	Ethanol ≤5000ppm Acetone ≤5000ppm Dichloromethane ≤600ppm n-Hexane ≤290ppm Ethyl acetate ≤5000ppm n-Heptane ≤5000ppm
Assay	95.0%~102.5%(anhydrous substance)

Description

Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with K_is of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases.

Safety Information

GHS

Pictogram:

GHS09 GHS07

Signal Word:

Danger

Hazard Statements:

H302 Harmful if swallowed.
H410 Very toxic to aquatic life with long lasting effects.

Precautionary Statements:

P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell.
P330 Rinse mouth.
P391 Collect spillage.
P501 Dispose of contents/ container to an approved waste disposal plant.