Latanoprost acid
CAS No:
41639-83-2
Molecular Formula：
C23H34O5
Molecular Weight：
390.51
Storage:
Store in a tightly closed container in a cool, dry，Protect from moisture and direct sunlight.
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Technical Data
| Appearance | Light yellow to brown liquid |
|---|---|
| Identification | NMR HPLC |
| Purity | ≥95% |
Description
Latanoprost acid, an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor. Latanoprost acid inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid is a medication which works to lower pressure inside the eyes.
Safety Information
GHS
Pictogram:
Signal Word:
Danger
Hazard Statements:
Causes serious eye irritation
May cause drowsiness or dizziness
Highly flammable liquid and vapor
Precautionary Statements:
Wash face, hands and any exposed skin thoroughly after
handling
Wear protective gloves/protective clothing/eye protection/faceprotection
Avoid breathing dust/fume/gas/mist/vapors/spray
Use only outdoors or in a well-ventilated area
Keepawayfromheat/sparks/openflames/hotsurfaces.—Nosmoking
Keep container tightly closed
Ground/bond container and receiving equipment
Use only non-sparking tools
Take precautionary measures against static dischargeKeep cool
IF exposed or concerned: Get medical advice/attentionIF IN EYES:
Rinse cautiously with water for several minutes. Remove contact lenses,
if present and easy to do. Continuerinsing
If eye irritation persists: Get medical advice/attentionIF ON SKIN (or hair):
Remove/Take off immediately all
contaminated clothing. Rinse skin with water/shower
IF INHALED: Remove victim to fresh air and keep at rest inaposition comfortable for breathing
Call a POISON CENTER or doctor/physician if you feel unwell
In case of fire: Use CO2, dry chemical, or foamfor extinction
Store in a well-ventilated place. Keep container tightlyclosedStore locked up
Dispose of contents/container to an approved wastedisposal
plant
References
1. Weinreb RN, et al. Effects of prostaglandins on the aqueous humor outflow pathways. Surv Ophthalmol. 2002 Aug;47 Suppl 1:S53-64.
2. Xu X, et al. The prevention of latanoprost on osteoclastgenesis in vitro and lipopolysaccharide-induced murine calvaria osteolysis in vivo. J Cell Biochem. 2018 Jun;119(6):4680-4691.
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