Bimatoprost acid

CAS No:

38344-08-0

Molecular Formula:

C23H32O5

Molecular Weight:

388.50

Storage:

Store in a tightly closed container in a cool, dry,Protect from moisture and direct sunlight.

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Technical Data

Appearance

White or almost white solid

Identification

NMR HPLC

Loss on drying

≤1.0%

5-trans impurity

≤ 2.50%

Purity(HPLC)

≥97.0%

Description

Bimatoprost acid (17-Phenyl trinor PGF2α), the acid hydrolysis product of Bimatoprost (HY-B0191), is a potent agonist of prostaglandin FP receptor

Safety Information

GHS

Pictogram:

GHS08GHS07

Signal Word:

Warning

Hazard Statements:

H361: Suspected of damaging fertility or the unborn child.

Precautionary Statements:

P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P280: Wear protective gloves / protective clothing / eye protection / face protection.
P308+P313: IF exposed or concerned: Get medical advice / attention.
P405: Store locked up.
P501: Dispose of contents / container in accordance with local / regional / national / international regulations.

References

1. Ichhpujani P, et al. Comparison of human ocular distribution of bimatoprost and latanoprost. J Ocul Pharmacol Ther. 2012 Apr;28(2):134-45.

2. Krauss AH, et al. Update on the mechanism of action of bimatoprost: a review and discussion of new evidence. Surv Ophthalmol. 2004 Mar;49 Suppl 1:S5-11.

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