D-Cloprostenol Sodium

CAS No:

62561-03-9

Molecular Formula:

C22H28ClNaO6

Molecular Weight:

446.90

Storage:

Store in a tightly closed container in a cool, dry, Protect from moisture and direct sunlight.

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Technical Data

Appearance

A white or almost white,amorphous powder;hygroscopic

Identification

IR,HPLC
White precipitate is observed in characteristic
testing of sodium salts

Solubility

Free soluble in water,in ethanol(95%)and in methanol;practically insoluble in acetone

Water

≤3.0%

15-epimer

≤0.5%

5,6-trans isomer

≤1.0%

Other single impurity

≤1.0%

Total impurities

≤2.5%

Residue solvents

Methnol≤0.3%
Tetrahydrofuran≤0.072%
Toluene≤0.089%
Ethyl acetate≤0.5%
Dichloromethane≤0.06%

Purity (HPLC)

≥98.5%

Assay (HPLC)

97.5~102.5%

Description

(+)-Cloprostenol sodium is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor.

Safety Information

GHS

Pictogram:

GHS07

Signal Word:

Warning

Hazard Statements:

H302 Harmful if swallowed

Precautionary Statements:

P264 Wash hands thoroughly after handling
P270 Do not eat, drink or smoke when using this product

References

[1]. Manca R, et al. Intra-vesicle administration of D-cloprostenol for induction of abortion in mid-gestation bitches. Anim Reprod Sci. 2008 Jun;106(1-2):133-42. Epub 2007 Apr 21.

[2]. Re G, et al. Specific binding of dl-cloprostenol and d-cloprostenol to PGF2 alpha receptors in bovine corpus luteum and myometrial cell membranes. J Vet Pharmacol Ther. 1994 Dec;17(6):455-8.

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